Student project: Simulating peripheral nerve stimulation

At IMEC (Thesis)

What you will do
Peripheral nerve systems connects organs and limbs to the central nervous system. This project aims to model peripheral nerve stimulation to develop methodology for spatially selective stimulation of peripheral nerves.

The peripheral nervous system (PNS) consists of the nerves outside of the central nervous system (CNS) and connects the CNS to the organs, limbs and skin. It is a two directional pathway between CNS and internal organs and hence can have powerful impact on the functionality of both. Currently, interest in peripheral nerve stimulation is growing as an alternative or a complement to pharmacological treatment, i.e., treatment with medication, for applications such as epilepsy, pain, depression, and inflammatory bowel disease.

 

One of the major challenges is specific spatial stimulation of only required population of neurons within the nerve that is needed for modulating the activity of specific organs. Avoiding unspecific stimulation can also result in minimizing unwanted site effects.

 

This project aims to develop methodology for spatially selective stimulation of peripheral nerves and local measurement of the stimulation effect within the nerves. To achieve this goal the student will perform a literature study, explore nerve modeling tools, and design and perform simulations for stimulation and sensing.

 

Tasks:

  • Literature review.
  • Develop a nerve model.
  • Design and perform simulations.
  • Analysis of simulation results.
  • Report and documentation, depending on results write a paper.

What we do for you
You will be working on cutting-edge research on a topic that is very relevant to both academic and industrial research groups. To help you in this journey, we offer a flexible environment where you can be the leader of your own research while at the same time have support of a team of multidisciplinary experts to complete your tasks.

IMEC has in-house experts in neuromonitoring and computational techniques who can help you in shaping this multi-disciplinary research project.

 

Who you are

  • You are a Msc student in Physics, (Neuro)Physiology, (Neuro)Biology.
  • You are available for a period of 9 months.
  • You have knowledge of computer simulations through course and/or project work.
  • You are excited about neurology.
  • You are entitled to do an internship in the Netherlands.
  • You are self-starter and able to work independently.
  • Good written and verbal English skills.

Interested
Click on 'apply' to submit your application. You will then be redirected to e-recruiting.

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